THE STUDY OF ESTABLISHMENT OF AN IN VIVO TUMOR MODEL BY THREE-DIMENSIONAL CELLS CULTURE SYSTEMS METHODS AND EVALUATION OF ANTITUMOR EFFECT OF BIOTIN-CONJUGATED PULLULAN ACETATE NANOPARTICLES

In this study, three-dimensional (3D) hydrogels were used for human Grill Side Rack hepatocellular carcinoma (HepG2) cells culture systems in vitro and establishment of an in vivo xenografted tumor model.Based on our previous work on the biotin-conjugated pullulan acetate nanoparticles (Bio-PA NPs) as anticancer drug carriers, we further studied th

Introduction: This review revisits clinical use of antibiotics for most common acute oro-dental conditions; we aim to provide evidence governing antibiotics use when access to oral healthcare is not available, as during the ongoing outbreak of the severe acute respiratory syndrome coronavirus 2.Materials and methods: In this rapid review, articles

The emergence of the capacity to digest milk in some populations represents a landmark in human evolution, linking genetic change with a component of niche construction, namely dairying.Alleles promoting continued activity of the enzyme lactase through the life-course (lactase persistence) evolved in several global regions within the last 7,000 yea

Abstract Background It is established that increasing the amplitude of a flutter stimulus increases its perceived intensity.Although many studies have examined this phenomenon with regard to the responding afferent population, the way in which the intensity of a stimulus is coded in primary Headlights somatosensory cortex (SI) remains unclear.Resul

We clarify two points made in our commentary (Pezzo & Beckstead, 2020, this issue) on a recent paper by Longoni, Bonezzi, and Morewedge (2019).In both Experiments 1 and 4 from their paper, it is not possible to determine whether accuracy can compensate for algorithm aversion.Experiments 3A-C, however, do show a strong effect of accuracy such that A